Journal of Clinical Oncology: Early Release Journal of Clinical Oncology will publish all articles on JCO.org in advance of print publication. The new policy will provide subscribers with the latest clinical research several weeks before it appears in print. All articles have been reviewed, copy edited, typeset and appear in the final form in which they will appear in the print journal. Once an article appears in print, it will be removed from the Early Release page and grouped the other contents of the issue in which it appears. All articles below are citable. Just use the Digital Object Identifier (DOI), a unique number given to every article, and the posting date. To see an article, click its [PDF] link. To review multiple abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. Next posting date: November 24, 2008 The following articles have been released: CELEBRATING 25 YEARS OF JCO EDITORIALS ORIGINAL REPORTS Breast Cancer Cancer-Related Complications Epidemiology Gastrointestinal Cancer Genetic Testing for Cancer Genitourinary Cancer Gynocologic Cancer Head and Neck Cancer Leukemia and Bone Marrow Transplantation Lymphoma and Myeloma Melanoma Neurooncology Palliative and Supportive Care Pediatric Oncology Phase I and Clinical Pharmacology Prevention Sarcomas Staging Supportive Care and Quality of Life Thoracic Oncology Treatment-Related Complications REVIEW ARTICLES BIOLOGY OF NEOPLASIA ASCO SPECIAL ARTICLES SPECIAL ARTICLE ART OF ONCOLOGY DIAGNOSIS IN ONCOLOGY CORRESPONDENCE CELEBRATING 25 YEARS OF JCO Lymphography: A Great Advance, Abandoned Saul A. Rosenberg * This is a commentary and, as such, does not have a full abstract. JCO published online November 10, 2008, 10.1200/JCO.2008.20.6946 [Abstract] [PDF] Retinol, Vitamins, and Cancer Prevention: 25 Years of Learning and Relearning Gary E. Goodman, David S. Alberts, and Frank L. Meyskens * This is a commentary and, as such, does not have a full abstract. JCO published online October 14, 2008, 10.1200/JCO.2008.19.0884 [Abstract] [PDF] [From JCO 1983] [top] EDITORIALS Practical Model for Prognostication in Advanced Cancer Patients: Is Less More? Eduardo Bruera and David Hui * This is an editorial and, as such, does not have a full abstract. JCO published online November 17, 2008, 10.1200/JCO.2008.19.7772 [Abstract] [PDF] Gene Testing to Predict Tamoxifen-Induced Hot Flashes: New Biological Insights Carolyn J. Crandall * This is an editorial and, as such, does not have a full abstract. JCO published online November 17, 2008, 10.1200/JCO.2008.19.5040 [Abstract] [PDF] Promoting Efficiency and Quality of Care in the Hummer Health Care System Karl A. Lorenz * This is an editorial and, as such, does not have a full abstract. JCO published online November 10, 2008, 10.1200/JCO.2008.18.2162 [Abstract] [PDF] Breast Cancer–Related Lymphedema: Attention to a Significant Problem Resulting From Cancer Diagnosis Electra D. Paskett * This is an editorial and, as such, does not have a full abstract. JCO published online November 10, 2008, 10.1200/JCO.2008.19.0850 [Abstract] [PDF] Using Predictive Biomarkers to Select Patients With Advanced Colorectal Cancer for Treatment With Epidermal Growth Factor Receptor Antibodies Rachel Wong and David Cunningham * This is an editorial and, as such, does not have a full abstract. JCO published online November 10, 2008, 10.1200/JCO.2008.19.5024 [Abstract] [PDF] Targeting Polo-Like Kinase: Learning Too Little Too Late? David Olmos, Charles Swanton, and Johann de Bono * This is an editorial and, as such, does not have a full abstract. JCO published online October 27, 2008, 10.1200/JCO.2008.18.6585 [Abstract] [PDF] Clinical Relevance of "Late" in the Management of Late Relapse After Treatment for a Germ Cell Tumor Guy C. Toner * This is an editorial and, as such, does not have a full abstract. JCO published online October 20, 2008, 10.1200/JCO.2008.18.7120 [Abstract] [PDF] Reirradiation and Concurrent Chemotherapy After Salvage Surgery: Pay Now or Pay Later Stuart J. Wong and Sharon Spencer * This is an editorial and, as such, does not have a full abstract. JCO published online October 20, 2008, 10.1200/JCO.2008.19.0868 [Abstract] [PDF] [top] ORIGINAL REPORTS Breast Cancer Estrogen Receptor Genotypes Influence Hot Flash Prevalence and Composite Score Before and After Tamoxifen Therapy Yan Jin, Daniel F. Hayes, Lang Li, Jason D. Robarge, Todd C. Skaar, Santosh Philips, Anne Nguyen, Anne Schott, Jill Hayden, Suzanne Lemler, Anna Maria Storniolo, David A. Flockhart, and Vered Stearns JCO published online November 17, 2008, 10.1200/JCO.2008.16.8377 [Abstract] [PDF] Intervals Longer Than 20 Weeks From Breast-Conserving Surgery to Radiation Therapy Are Associated With Inferior Outcome for Women With Early-Stage Breast Cancer Who Are Not Receiving Chemotherapy Ivo A. Olivotto, Mary L. Lesperance, Pauline T. Truong, Alan Nichol, Tanya Berrang, Scott Tyldesley, François Germain, Caroline Speers, Elaine Wai, Caroline Holloway, Winkle Kwan, and Hagen Kennecke JCO published online November 17, 2008, 10.1200/JCO.2008.18.1891 [Abstract] [PDF] Human Epidermal Growth Factor Receptor 2 Overexpression As a Prognostic Factor in a Large Tissue Microarray Series of Node-Negative Breast Cancers Stephen Chia, Brian Norris, Caroline Speers, Maggie Cheang, Blake Gilks, Allen M. Gown, David Huntsman, Ivo A. Olivotto, Torsten O. Nielsen, and Karen Gelmon JCO published online November 10, 2008, 10.1200/JCO.2007.15.8659 [Abstract] [PDF] Lymphedema and Quality of Life in Breast Cancer Survivors: The Iowa Women's Health Study Rehana L. Ahmed, Anna Prizment, DeAnn Lazovich, Kathryn H. Schmitz, and Aaron R. Folsom JCO published online November 10, 2008, 10.1200/JCO.2008.16.4731 [Abstract] [PDF] Prognostic and Predictive Value of Centrally Reviewed Ki-67 Labeling Index in Postmenopausal Women With Endocrine-Responsive Breast Cancer: Results From Breast International Group Trial 1-98 Comparing Adjuvant Tamoxifen With Letrozole Giuseppe Viale, Anita Giobbie-Hurder, Meredith M. Regan, Alan S. Coates, Mauro G. Mastropasqua, Patrizia Dell'Orto, Eugenio Maiorano, Gaëtan MacGrogan, Stephen G. Braye, Christian Öhlschlegel, Patrick Neven, Zsolt Orosz, Wojciech P. Olszewski, Fiona Knox, Beat Thürlimann, Karen N. Price, Monica Castiglione-Gertsch, Richard D. Gelber, Barry A. Gusterson, and Aron Goldhirsch JCO published online November 3, 2008, 10.1200/JCO.2008.17.0829 [Abstract] [PDF] Phase III, Double-Blind, Randomized Study Comparing Lapatinib Plus Paclitaxel With Placebo Plus Paclitaxel As First-Line Treatment for Metastatic Breast Cancer Angelo Di Leo, Henry L. Gomez, Zeba Aziz, Zanete Zvirbule, Jose Bines, Michael C. Arbushites, Stephanie F. Guerrera, Maria Koehler, Cristina Oliva, Steven H. Stein, Lisa S. Williams, Judy Dering, Richard S. Finn, and Michael F. Press JCO published online October 27, 2008, 10.1200/JCO.2008.16.2578 [Abstract] [PDF] Chemotherapy Use for Hormone Receptor–Positive, Lymph Node–Negative Breast Cancer Michael J. Hassett, Melissa E. Hughes, Joyce C. Niland, Stephen B. Edge, Richard L. Theriault, Yu-Ning Wong, John Wilson, W. Bradford Carter, Douglas W. Blayney, and Jane C. Weeks JCO published online October 27, 2008, 10.1200/JCO.2008.17.9705 [Abstract] [PDF] Roles of Radiotherapy and Chemotherapy in the Development of Contralateral Breast Cancer Maartje J. Hooning, Berthe M.P. Aleman, Michael Hauptmann, Margreet H.A. Baaijens, Jan G.M. Klijn, Ruth Noyon, Marilyn Stovall, and Flora E. van Leeuwen JCO published online October 14, 2008, 10.1200/JCO.2007.16.0192 [Abstract] [PDF] [top] Cancer-Related Complications Natural History of Osteonecrosis of the Jaw in Patients With Multiple Myeloma Ashraf Badros, Evangelos Terpos, Eirini Katodritou, Olga Goloubeva, Efstathios Kastritis, Evgenia Verrou, Kostas Zervas, Maria R. Baer, Timothy Meiller, and Meletios A. Dimopoulos JCO published online November 17, 2008, 10.1200/JCO.2008.16.9300 [Abstract] [PDF] [top] Epidemiology Plasma Isoflavones and Subsequent Risk of Prostate Cancer in a Nested Case-Control Study: The Japan Public Health Center Norie Kurahashi, Motoki Iwasaki, Manami Inoue, Shizuka Sasazuki, and Shoichiro Tsugane JCO published online November 17, 2008, 10.1200/JCO.2008.16.8807 [Abstract] [PDF] [top] Gastrointestinal Cancer Efficacy of Oxaliplatin Plus Capecitabine or Infusional Fluorouracil/Leucovorin in Patients With Metastatic Colorectal Cancer: A Pooled Analysis of Randomized Trials Hendrik-Tobias Arkenau, Dirk Arnold, Jim Cassidy, Eduardo Diaz-Rubio, Jean-Yves Douillard, Howard Hochster, Andrea Martoni, Axel Grothey, Axel Hinke, Wolff Schmiegel, Hans-Joachim Schmoll, and Rainer Porschen JCO published online November 17, 2008, 10.1200/JCO.2008.16.7759 [Abstract] [PDF] Wild-Type BRAF Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer Federica Di Nicolantonio, Miriam Martini, Francesca Molinari, Andrea Sartore-Bianchi, Sabrina Arena, Piercarlo Saletti, Sara De Dosso, Luca Mazzucchelli, Milo Frattini, Salvatore Siena, and Alberto Bardelli JCO published online November 10, 2008, 10.1200/JCO.2008.18.0786 [Abstract] [PDF] Five-Year Data and Prognostic Factor Analysis of Oxaliplatin and Irinotecan Combinations for Advanced Colorectal Cancer: N9741 Hanna K. Sanoff, Daniel J. Sargent, Megan E. Campbell, Roscoe F. Morton, Charles S. Fuchs, Ramesh K. Ramanathan, Stephen K. Williamson, Brian P. Findlay, Henry C. Pitot, and Richard M. Goldberg JCO published online November 10, 2008, 10.1200/JCO.2008.17.7147 [Abstract] [PDF] Cohort Study of Fatty Acid Synthase Expression and Patient Survival in Colon Cancer Shuji Ogino, Katsuhiko Nosho, Jeffrey A. Meyerhardt, Gregory J. Kirkner, Andrew T. Chan, Takako Kawasaki, Edward L. Giovannucci, Massimo Loda, and Charles S. Fuchs JCO published online October 27, 2008, 10.1200/JCO.2008.18.2675 [Abstract] [PDF] [top] Genetic Testing for Cancer Physicians' Experiences With BRCA1/2 Testing in Community Settings Nancy L. Keating, Kathryn A. Stoeckert, Meredith M. Regan, Lisa DiGianni, and Judy E. Garber JCO published online November 10, 2008, 10.1200/JCO.2008.17.8053 [Abstract] [PDF] Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer Heather Hampel, Wendy L. Frankel, Edward Martin, Mark Arnold, Karamjit Khanduja, Philip Kuebler, Mark Clendenning, Kaisa Sotamaa, Thomas Prior, Judith A. Westman, Jenny Panescu, Dan Fix, Janet Lockman, Jennifer LaJeunesse, Ilene Comeras, and Albert de la Chapelle JCO published online September 8, 2008, 10.1200/JCO.2008.17.5950 [Abstract] [PDF] [top] Genitourinary Cancer [18F]Fluorodeoxyglucose Positron Emission Tomography in Nonseminomatous Germ Cell Tumors After Chemotherapy: The German Multicenter Positron Emission Tomography Study Group Karin Oechsle, Michael Hartmann, Winfried Brenner, Stephan Venz, Lothar Weissbach, Christiane Franzius, Sabine Kliesch, Stephan Mueller, Susanne Krege, Ruediger Heicappell, Roland Bares, Carsten Bokemeyer, and Maike de Wit JCO published online November 17, 2008, 10.1200/JCO.2008.17.1157 [Abstract] [PDF] Clinical Outcome and Predictors of Survival in Late Relapse of Germ Cell Tumor David S. Sharp, Brett S. Carver, Scott E. Eggener, G. Varuni Kondagunta, Robert J. Motzer, George J. Bosl, and Joel Sheinfeld JCO published online October 20, 2008, 10.1200/JCO.2007.15.7453 [Abstract] [PDF] [top] Gynocologic Cancer Phase II Study of Carboplatin and Pemetrexed for the Treatment of Platinum-Sensitive Recurrent Ovarian Cancer Ursula A. Matulonis, Neil S. Horowitz, Susana M. Campos, Hang Lee, Julie Lee, Carolyn N. Krasner, Suzanne Berlin, Maria R. Roche, Linda R. Duska, Lauren Pereira, Deborah Kendall, and Richard T. Penson JCO published online November 10, 2008, 10.1200/JCO.2008.17.0282 [Abstract] [PDF] Carcinoma of the Lower Uterine Segment: A Newly Described Association With Lynch Syndrome Shannon N. Westin, Robin A. Lacour, Diana L. Urbauer, Rajyalakshmi Luthra, Diane C. Bodurka, Karen H. Lu, and Russell R. Broaddus JCO published online November 10, 2008, 10.1200/JCO.2008.18.6296 [Abstract] [PDF] "BRCAness" Syndrome in Ovarian Cancer: A Case-Control Study Describing the Clinical Features and Outcome of Patients With Epithelial Ovarian Cancer Associated With BRCA1 and BRCA2 Mutations David S.P. Tan, Christian Rothermundt, Karen Thomas, Elizabeth Bancroft, Rosalind Eeles, Susan Shanley, Audrey Ardern-Jones, Andrew Norman, Stanley B. Kaye, and Martin E. Gore JCO published online October 27, 2008, 10.1200/JCO.2008.16.1703 [Abstract] [PDF] [top] Head and Neck Cancer Randomized Trial of Postoperative Reirradiation Combined With Chemotherapy After Salvage Surgery Compared With Salvage Surgery Alone in Head and Neck Carcinoma François Janot, Dominique de Raucourt, Ellen Benhamou, Christophe Ferron, Gilles Dolivet, René-Jean Bensadoun, Marc Hamoir, Bernard Géry, Morbize Julieron, Marine Castaing, Etienne Bardet, Vincent Grégoire, and Jean Bourhis JCO published online October 20, 2008, 10.1200/JCO.2007.15.0102 [Abstract] [PDF] [top] Leukemia and Bone Marrow Transplantation Relationship of Treatment-Related Cytopenias and Response to Lenalidomide in Patients With Lower-Risk Myelodysplastic Syndromes Mikkael A. Sekeres, Jaroslaw P. Maciejewski, Aristotle A.N. Giagounidis, Kenton Wride, Robert Knight, Azra Raza, and Alan F. List JCO published online November 17, 2008, 10.1200/JCO.2007.15.5770 [Abstract] [PDF] Association of Serum Interleukin-7 Levels With the Development of Acute Graft-Versus-Host Disease Robert M. Dean, Terry Fry, Crystal Mackall, Seth M. Steinberg, Fran Hakim, Daniel Fowler, Jeanne Odom, Jason Foley, Ronald Gress, and Michael R. Bishop JCO published online November 10, 2008, 10.1200/JCO.2008.17.1314 [Abstract] [PDF] Risk Factors for Acute Graft-Versus-Host Disease After Human Leukocyte Antigen–Identical Sibling Transplants for Adults With Leukemia Theresa Hahn, Philip L. McCarthy Jr, Mei-Jie Zhang, Dan Wang, Mukta Arora, Haydar Frangoul, Robert Peter Gale, Gregory A. Hale, John Horan, Luis Isola, Richard T. Maziarz, Jon J. van Rood, Vikas Gupta, Joerg Halter, Vijay Reddy, Pierre Tiberghien, Mark Litzow, Claudio Anasetti, Stephen Pavletic, and Olle Ringdén JCO published online November 3, 2008, 10.1200/JCO.2008.17.6545 [Abstract] [PDF] [top] Lymphoma and Myeloma Risk-Adapted Salvage Treatment With Single or Tandem Autologous Stem-Cell Transplantation for First Relapse/Refractory Hodgkin's Lymphoma: Results of the Prospective Multicenter H96 Trial by the GELA/SFGM Study Group Franck Morschhauser, Pauline Brice, Christophe Fermé, Marine Diviné, Gilles Salles, Reda Bouabdallah, Catherine Sebban, Laurent Voillat, Olivier Casasnovas, Aspasia Stamatoullas, Krimo Bouabdallah, Marc André, Jean-Philippe Jais, Dominique Cazals-Hatem, and Christian Gisselbrecht JCO published online November 17, 2008, 10.1200/JCO.2007.15.5887 [Abstract] [PDF] Improved Survival in Lymphoma Patients Receiving Sirolimus for Graft-Versus-Host Disease Prophylaxis After Allogeneic Hematopoietic Stem-Cell Transplantation With Reduced-Intensity Conditioning Philippe Armand, Supriya Gannamaneni, Haesook T. Kim, Corey S. Cutler, Vincent T. Ho, John Koreth, Edwin P. Alyea, Ann S. LaCasce, Eric D. Jacobsen, David C. Fisher, Jennifer R. Brown, George P. Canellos, Arnold S. Freedman, Robert J. Soiffer, and Joseph H. Antin JCO published online November 10, 2008, 10.1200/JCO.2008.17.7279 [Abstract] [PDF] Influence of Pre- and Post-Transplantation Responses on Outcome of Patients With Multiple Myeloma: Sequential Improvement of Response and Achievement of Complete Response Are Associated With Longer Survival Juan José Lahuerta, Maria Victoria Mateos, Joaquin Martínez-López, Laura Rosiñol, Anna Sureda, Javier de la Rubia, José García-Laraña, Rafael Martínez-Martínez, Miguel T. Hernández-García, Dolores Carrera, Joan Besalduch, Felipe de Arriba, José María Ribera, Lourdes Escoda, Belén Hernández-Ruiz, Javier García-Frade, Concepción Rivas-González, Adrían Alegre, Joan Bladé, and Jesús F. San Miguel JCO published online November 10, 2008, 10.1200/JCO.2008.17.9721 [Abstract] [PDF] [top] Melanoma Phase I/II Study of Ipilimumab for Patients With Metastatic Melanoma Jeffrey S. Weber, Steven O'Day, Walter Urba, John Powderly, Geoff Nichol, Michael Yellin, Jolie Snively, and Evan Hersh JCO published online November 17, 2008, 10.1200/JCO.2008.16.1927 [Abstract] [PDF] Phase III Trial Comparing Concurrent Biochemotherapy With Cisplatin, Vinblastine, Dacarbazine, Interleukin-2, and Interferon Alfa-2b With Cisplatin, Vinblastine, and Dacarbazine Alone in Patients With Metastatic Malignant Melanoma (E3695): A Trial Coordinated by the Eastern Cooperative Oncology Group Michael B. Atkins, Jessie Hsu, Sandra Lee, Gary I. Cohen, Lawrence E. Flaherty, Jeffrey A. Sosman, Vernon K. Sondak, and John M. Kirkwood JCO published online November 10, 2008, 10.1200/JCO.2008.17.5448 [Abstract] [PDF] Impact of Molecular Staging Methods in Primary Melanoma: Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) of Ultrasound-Guided Aspirate of the Sentinel Node Does Not Improve Diagnostic Accuracy, But RT-PCR of Peripheral Blood Does Predict Survival Christiane A. Voit, Gregor Schäfer-Hesterberg, Martina Kron, Alexander C.J. van Akkooi, Juergen Rademaker, Ansgar Lukowsky, Alfred Schoengen, Markus Schwürzer-Voit, Wolfram Sterry, Markus Krause, Joachim Röwert-Huber, and Alexander M.M. Eggermont JCO published online November 3, 2008, 10.1200/JCO.2007.13.7653 [Abstract] [PDF] [top] Neurooncology Polymorphism in the Microglial Cell-Mobilizing CX3CR1 Gene Is Associated With Survival in Patients With Glioblastoma Mathieu Rodero, Yannick Marie, Mathieu Coudert, Emmeline Blondet, Karima Mokhtari, Audrey Rousseau, William Raoul, Catherine Carpentier, Florian Sennlaub, Philippe Deterre, Jean-Yves Delattre, Patrice Debré, Marc Sanson, and Christophe Combadière JCO published online November 10, 2008, 10.1200/JCO.2008.17.2833 [Abstract] [PDF] Randomized Phase II Study of Cilengitide, an Integrin-Targeting Arginine-Glycine-Aspartic Acid Peptide, in Recurrent Glioblastoma Multiforme David A. Reardon, Karen L. Fink, Tom Mikkelsen, Timothy F. Cloughesy, Alison O'Neill, Scott Plotkin, Michael Glantz, Paula Ravin, Jeffrey J. Raizer, Keith M. Rich, David Schiff, William R. Shapiro, Susan Burdette-Radoux, Edward J. Dropcho, Sabine M. Wittemer, Johannes Nippgen, Martin Picard, and L. Burt Nabors JCO published online November 3, 2008, 10.1200/JCO.2008.16.7510 [Abstract] [PDF] Phase I/II Trial Erlotinib and Temozolomide With Radiation Therapy in the Treatment of Newly Diagnosed Glioblastoma Multiforme: North Central Cancer Treatment Group Study N0177 Paul D. Brown, Sunil Krishnan, Jann N. Sarkaria, Wenting Wu, Kurt A. Jaeckle, Joon H. Uhm, Francois J. Geoffroy, Robert Arusell, Gaspar Kitange, Robert B. Jenkins, John W. Kugler, Roscoe F. Morton, Kendrith M. Rowland Jr, Paul Mischel, William H. Yong, Bernd W. Scheithauer, David Schiff, Caterina Giannini, and Jan C. Buckner JCO published online October 27, 2008, 10.1200/JCO.2008.18.0612 [Abstract] [PDF] [top] Palliative and Supportive Care Predictive Model for Survival in Patients With Advanced Cancer Edward Chow, Mohamed Abdolell, Tony Panzarella, Kristin Harris, Andrea Bezjak, Padraig Warde, and Ian Tannock JCO published online November 17, 2008, 10.1200/JCO.2008.17.1363 [Abstract] [PDF] Comparison of Prospective and Retrospective Indicators of the Quality of End-of-Life Cancer Care Soko Setoguchi, Craig C. Earle, Robert Glynn, Margaret Stedman, Jennifer M. Polinski, Colleen P. Corcoran, and Jennifer S. Haas JCO published online November 10, 2008, 10.1200/JCO.2008.16.3956 [Abstract] [PDF] Changes in the Quantity and Level of Evidence of Palliative and Hospice Care Literature: The Last Century Jennifer Tieman, Ruth Sladek, and David Currow JCO published online November 10, 2008, 10.1200/JCO.2008.17.6230 [Abstract] [PDF] [top] Pediatric Oncology Impact of Disease Risk on Efficacy of Matched Related Bone Marrow Transplantation for Pediatric Acute Myeloid Leukemia: The Children's Oncology Group John T. Horan, Todd A. Alonzo, Gary H. Lyman, Robert B. Gerbing, Beverly J. Lange, Yaddanapudi Ravindranath, David Becton, Franklin O. Smith, and William G. Woods JCO published online October 27, 2008, 10.1200/JCO.2007.13.5244 [Abstract] [PDF] [top] Phase I and Clinical Pharmacology Phase I Study of ON 01910.Na, a Novel Modulator of the Polo-Like Kinase 1 Pathway, in Adult Patients With Solid Tumors Antonio Jimeno, Jing Li, Wells A. Messersmith, Daniel Laheru, Michelle A. Rudek, Manoj Maniar, Manuel Hidalgo, Sharyn D. Baker, and Ross C. Donehower JCO published online October 27, 2008, 10.1200/JCO.2008.17.9788 [Abstract] [PDF] Phase I Dose Escalation and Pharmacokinetic Study of BI 2536, a Novel Polo-Like Kinase 1 Inhibitor, in Patients With Advanced Solid Tumors Klaus Mross, Annette Frost, Simone Steinbild, Susanne Hedbom, Jochen Rentschler, Rolf Kaiser, Nicolas Rouyrre, Dirk Trommeshauser, Cornelia E. Hoesl, and Gerd Munzert JCO published online October 27, 2008, 10.1200/JCO.2008.16.1547 [Abstract] [PDF] [top] Prevention Body-Mass Index and Progression of Hepatitis B: A Population-Based Cohort Study in Men Ming-Whei Yu, Wei-Liang Shih, Chih-Lin Lin, Chun-Jen Liu, Jhih-Wei Jian, Keh-Sung Tsai, and Chien-Jen Chen JCO published online October 27, 2008, 10.1200/JCO.2008.16.1075 [Abstract] [PDF] [top] Sarcomas Randomized, Phase II Study of the Thrombospondin-1-Mimetic Angiogenesis Inhibitor ABT-510 in Patients With Advanced Soft Tissue Sarcoma Laurence H. Baker, Eric K. Rowinsky, David Mendelson, Rod A. Humerickhouse, Raymond A. Knight, Jiang Qian, Robert A. Carr, Gary B. Gordon, and George D. Demetri JCO published online November 3, 2008, 10.1200/JCO.2008.17.4706 [Abstract] [PDF] [top] Staging Correlation of Kinase Genotype and Clinical Outcome in the North American Intergroup Phase III Trial of Imatinib Mesylate for Treatment of Advanced Gastrointestinal Stromal Tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group Michael C. Heinrich, Kouros Owzar, Christopher L. Corless, Donna Hollis, Ernest C. Borden, Christopher D.M. Fletcher, Christopher W. Ryan, Margaret von Mehren, Charles D. Blanke, Cathryn Rankin, Robert S. Benjamin, Vivien H. Bramwell, George D. Demetri, Monica M. Bertagnolli, and Jonathan A. Fletcher JCO published online October 27, 2008, 10.1200/JCO.2008.17.4284 [Abstract] [PDF] [top] Supportive Care and Quality of Life Randomized Comparison of Cooked and Noncooked Diets in Patients Undergoing Remission Induction Therapy for Acute Myeloid Leukemia Alison Gardner, Gloria Mattiuzzi, Stefan Faderl, Gautam Borthakur, Guillermo Garcia-Manero, Sherry Pierce, Mark Brandt, and Elihu Estey JCO published online October 27, 2008, 10.1200/JCO.2008.16.4681 [Abstract] [PDF] [top] Thoracic Oncology Effect of BRCA1 Haplotype on Survival of Non–Small-Cell Lung Cancer Patients Treated With Platinum-Based Chemotherapy Hong-Tae Kim, Jong-Eun Lee, Eun-Soon Shin, Yeon-Kyeong Yoo, Jae-Hwa Cho, Min-Hye Yun, Yeul-Hong Kim, Se-Kyu Kim, Hyun-Jung Kim, Tae-Won Jang, Seung-Min Kwak, Chul-Soo Kim, and Jeong-Seon Ryu JCO published online November 17, 2008, 10.1200/JCO.2008.16.6496 [Abstract] [PDF] Phase III Study of Cisplatin, Etoposide, and Concurrent Chest Radiation With or Without Consolidation Docetaxel in Patients With Inoperable Stage III Non–Small-Cell Lung Cancer: The Hoosier Oncology Group and U.S. Oncology Nasser Hanna, Marcus Neubauer, Constantin Yiannoutsos, Ronald McGarry, James Arseneau, Rafat Ansari, Craig Reynolds, Ramaswamy Govindan, Anton Melnyk, William Fisher, Donald Richards, Daniel Bruetman, Thomas Anderson, Naveed Chowhan, Sreenivasa Nattam, Prasad Mantravadi, Cynthia Johnson, Tim Breen, Angela White, and Lawrence Einhorn JCO published online November 10, 2008, 10.1200/JCO.2008.17.7840 [Abstract] [PDF] Circulating 25-Hydroxyvitamin D, VDR Polymorphisms, and Survival in Advanced Non–Small-Cell Lung Cancer Rebecca Suk Heist, Wei Zhou, Zhaoxi Wang, Geoffrey Liu, Donna Neuberg, Li Su, Kofi Asomaning, Bruce W. Hollis, Thomas J. Lynch, John C. Wain, Edward Giovannucci, and David C. Christiani JCO published online October 20, 2008, 10.1200/JCO.2008.18.0406 [Abstract] [PDF] EGFR Mutations Predict Survival Benefit From Gefitinib in Patients With Advanced Lung Adenocarcinoma: A Historical Comparison of Patients Treated Before and After Gefitinib Approval in Japan Toshimi Takano, Tomoya Fukui, Yuichiro Ohe, Koji Tsuta, Seiichiro Yamamoto, Hiroshi Nokihara, Noboru Yamamoto, Ikuo Sekine, Hideo Kunitoh, Koh Furuta, and Tomohide Tamura JCO published online September 15, 2008, 10.1200/JCO.2008.16.7254 [Abstract] [PDF] [top] Treatment-Related Complications Late Congestive Heart Failure After Hematopoietic Cell Transplantation Saro H. Armenian, Can-Lan Sun, Liton Francisco, Julia Steinberger, Seira Kurian, F. Lennie Wong, Jon Sharp, Richard Sposto, Stephen J. Forman, and Smita Bhatia JCO published online September 22, 2008, 10.1200/JCO.2008.17.7428 [Abstract] [PDF] [top] REVIEW ARTICLES Reducing Uncertainties About the Effects of Chemoradiotherapy for Cervical Cancer: A Systematic Review and Meta-Analysis of Individual Patient Data From 18 Randomized Trials Chemoradiotherapy for Cervical Cancer Meta-Analysis Collaboration JCO published online November 10, 2008, 10.1200/JCO.2008.16.4368 [Abstract] [PDF] Nonpharmacologic Strategies for Managing Common Chemotherapy Adverse Effects: A Systematic Review Kerryann Lotfi-Jam, Mariko Carey, Michael Jefford, Penelope Schofield, Catherine Charleson, and Sanchia Aranda JCO published online November 3, 2008, 10.1200/JCO.2007.15.9053 [Abstract] [PDF] [top] BIOLOGY OF NEOPLASIA A Decade of Tissue Microarrays: Progress in the Discovery and Validation of Cancer Biomarkers Robert L. Camp, Veronique Neumeister, and David L. Rimm JCO published online October 20, 2008, 10.1200/JCO.2008.17.3567 [Abstract] [PDF] [top] ASCO SPECIAL ARTICLES American Society of Clinical Oncology 2008 Clinical Practice Guideline Update: Use of Chemotherapy and Radiation Therapy Protectants Martee L. Hensley, Karen L. Hagerty, Tarun Kewalramani, Daniel M. Green, Neal J. Meropol, Todd H. Wasserman, Gary I. Cohen, Bahman Emami, William J. Gradishar, R. Brian Mitchell, J. Tate Thigpen, Andy Trotti III, Daniel von Hoff, and Lynn M. Schuchter JCO published online October 27, 2008, 10.1200/JCO.2008.17.2627 [Abstract] [PDF] [top] SPECIAL ARTICLE Recommendations for Collection and Handling of Specimens From Group Breast Cancer Clinical Trials Brian R. Leyland-Jones, Christine B. Ambrosone, John Bartlett, Matthew J.C. Ellis, Rebecca A. Enos, Adekunle Raji, Michael R. Pins, Jo Anne Zujewski, Stephen M. Hewitt, John F. Forbes, Mark Abramovitz, Sofia Braga, Fatima Cardoso, Nadia Harbeck, Carsten Denkert, and Scott D. Jewell JCO published online October 27, 2008, 10.1200/JCO.2007.15.1712 [Abstract] [PDF] [Data Supplement] [top] ART OF ONCOLOGY Surprised by Hope Prudence A. Francis JCO published online November 17, 2008, 10.1200/JCO.2008.19.0454 [PDF] [top] DIAGNOSIS IN ONCOLOGY Incidental Detection of Concurrent Extramedullary Plasmacytoma and Amyloidoma of the Nasopharynx on [18F]Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Akihiko Yoshida, Sunita Borkar, Bhuvanesh Singh, Ronald A. Ghossein, and Heiko Schöder JCO published online November 10, 2008, 10.1200/JCO.2008.18.6338 [PDF] Extragonadal Choriocarcinoma in Ulcerative Colitis Avanthi Ragam, Seema Apichai, Abhilasha Radhakrishnan, Miguel Gonzalez, Timothy Laurie, and Chadi Nabhan JCO published online November 10, 2008, 10.1200/JCO.2008.19.0264 [PDF] Synchronous Presentation of Multiple Myeloma and Lung Cancer Rishu Agarwal, Ritu Gupta, Archana Bhaskar, Atul Sharma, Sanjay Thulkar, and Lalit Kumar JCO published online November 10, 2008, 10.1200/JCO.2008.19.6287 [PDF] Multiple Myeloma Presenting With a Colonic Obstruction and Bony Lesions: A Clinical Dilemma Anne Herbst, Stephen W. Renner, Q. Scott Ringenberg, Ronnie Fass, and Robert S. Krouse JCO published online November 3, 2008, 10.1200/JCO.2008.18.6239 [PDF] Bevacizumab Reverses Cerebral Radiation Necrosis Eric T. Wong, Mark Huberman, Xing-Qi Lu, and Anand Mahadevan JCO published online November 3, 2008, 10.1200/JCO.2008.19.1866 [PDF] Late Relapsing Stage I Nonseminoma Carmel J. Pezaro, Girish Mallesara, and Guy C. Toner JCO published online November 3, 2008, 10.1200/JCO.2008.19.3417 [PDF] [top] CORRESPONDENCE "Groovy" Vaccine for Melanoma—But Which Groove? Sandra L. Nehlsen-Cannarella JCO published online November 17, 2008, 10.1200/JCO.2008.19.4886 [PDF] In Reply Jeffrey A. Sosman JCO published online November 17, 2008, 10.1200/JCO.2008.19.5578 [PDF] The Rotterdam Criteria for Sentinel Node Tumor Load: The Simplest Prognostic Factor? Alexander C.J. van Akkooi, Johannes H.W. de Wilt, Cornelis Verhoef, and Alexander M.M. Eggermont JCO published online November 17, 2008, 10.1200/JCO.2008.19.5420 [PDF] In Reply Jeffrey E. Gershenwald, Robert H. I. Andtbacka, and Merrick I. Ross JCO published online November 17, 2008, 10.1200/JCO.2008.19.5586 [PDF] Tumor Biology and Prognosis of Gastrointestinal Carcinoids Hans Scherübl JCO published online November 17, 2008, 10.1200/JCO.2008.19.9711 [PDF] In Reply James C. Yao JCO published online November 17, 2008, 10.1200/JCO.2008.20.0014 [PDF] Mediterranean Lifestyle Should Affect Health-Related Quality of Life Among Cancer Survivors Tommaso Cai, Nicola Mondaini, and Riccardo Bartoletti JCO published online November 17, 2008, 10.1200/JCO.2008.20.1871 [PDF] In Reply Kevin Stein, Chris M. Blanchard, Kerry S. Courneya, and Colleen Doyle JCO published online November 17, 2008, 10.1200/JCO.2008.20.2317 [PDF] Is Alemtuzumab Really the Single Active Agent for Treatment of Chronic Lymphocytic Leukemia? Satinderjit S. Oberoi and Rony M. Abou Jawde JCO published online November 10, 2008, 10.1200/JCO.2007.15.7537 [PDF] In Reply Peter Hillmen JCO published online November 10, 2008, 10.1200/JCO.2007.15.8584 [PDF] Paradoxical Clinical Effects of Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitors for Acute Myelogenous Leukemia Katsuyuki Hotta, Katsuyuki Kiura, Nagio Takigawa, Keitaro Matsuo, Masahiro Tabata, Yoshiro Fujiwara, and Mitsune Tanimoto JCO published online November 10, 2008, 10.1200/JCO.2008.19.5685 [PDF] In Reply Vincenzo Pitini, Carmela Arrigo, and Giuseppe Altavilla JCO published online November 10, 2008, 10.1200/JCO.2008.19.6204 [PDF] Does ER-βcx Really Have No Clinical Importance in Tamoxifen-Treated Breast Cancer Patients? Carlo Palmieri, Ondrej Gojis, Bharath Rudraraju, and Susan Cleator JCO published online November 10, 2008, 10.1200/JCO.2008.19.5529 [PDF] Clinical Importance of Estrogen Receptor β Isoforms in Breast Cancer Valerie Speirs, Andrew R. Green, Thomas A. Hughes, Ian O. Ellis, Philippa T.K. Saunders, and Abeer M. Shaaban JCO published online November 10, 2008, 10.1200/JCO.2008.19.5909 [PDF] In Reply Naoko Honma, Shigehira Saji, and Mamoun Younes JCO published online November 10, 2008, 10.1200/JCO.2008.19.6212 [PDF] Cost Effectiveness of Sunitinib Sabrina Trippoli and Andrea Messori JCO published online November 10, 2008, 10.1200/JCO.2008.19.8101 [PDF] In Reply Edit Remák JCO published online November 10, 2008, 10.1200/JCO.2008.19.8499 [PDF] Pleomorphic Lobular Carcinoma of the Breast: Four Long-Term Responders to Trastuzumab—Coincidence or Hint? Reshma L. Mahtani and Charles L. Vogel JCO published online November 10, 2008, 10.1200/JCO.2008.19.8226 [PDF] Cooperative Relationship Between Pharmaceutical Companies, Academia, and Media Explains Sharp Decrease in Frequency of Pulmonary Complications After Bortezomib in Japan Hiroto Narimatsu, Akiko Hori, Tomoko Matsumura, Yuko Kodama, Morihito Takita, Yukiko Kishi, Tamae Hamaki, Koichiro Yuji, Yuji Tanaka, Tsunehiko Komatsu, and Masahiro Kami JCO published online November 10, 2008, 10.1200/JCO.2008.20.3307 [PDF] Temsirolimus in Patients With Renal Cancer on Hemodialysis Gianluigi Lunardi, Maria Ornella Vannozzi, Andrea Armirotti, Maurizio Nicodemo, Marco Venturini, and Lucia Cavallini JCO published online November 3, 2008, 10.1200/JCO.2008.19.3144 [PDF] In Reply James Brugarolas JCO published online November 3, 2008, 10.1200/JCO.2008.19.4670 [PDF] Value of Positron Emission Tomography of the Para-Aortic Lymph Nodes in Cervical Carcinoma Stage IB2-IIIB Ignace Vergote, Dimitris Tsolakidis, Dieter Mortier, Patrick Neven, Frederic Amant, Felix Mottaghy, and Erik Van Limbergen JCO published online November 3, 2008, 10.1200/JCO.2008.19.5883 [PDF] In Reply Philippe Morice, Enrica Bentivegna, Catherine Uzan, Sebastien Gouy, Martin Schlumberger, Pierre Duvillard, and Christine Haie-Meder JCO published online November 3, 2008, 10.1200/JCO.2008.19.7707 [PDF] Management of Tumor Lysis Syndrome: Need for Evidence-Based Guidelines James H. Feusner, A. Kim Ritchey, Susan L. Cohn, and Amy L. Billett JCO published online November 3, 2008, 10.1200/JCO.2008.19.6030 [PDF] In Reply Bertrand Coiffier, Arnold Altman, Ching-Hon Pui, Anas Younes, and Mitchell S. Cairo JCO published online November 3, 2008, 10.1200/JCO.2008.19.7673 [PDF] Carcinoembryonic Antigen Monitoring in Metastatic Colorectal Cancer: Words of Caution Marwan G. Fakih JCO published online November 3, 2008, 10.1200/JCO.2008.19.6451 [PDF] In Reply Isabelle Iwanicki-Caron, Frederic Di Fiore, and Pierre Michel JCO published online November 3, 2008, 10.1200/JCO.2008.19.7699 [PDF] Personalized Medicine in Advanced Non–Small-Cell Lung Cancer: Reality or Wishful Thinking? Filip Janku and Brian Bird JCO published online October 20, 2008, 10.1200/JCO.2008.19.5164 [PDF] In Reply Giorgio V. Scagliotti and Katherine P. Sugarman JCO published online October 20, 2008, 10.1200/JCO.2008.19.5560 [PDF] [top]