EDITORIAL

Genomic Profiling of Cancer: What Next?

Paul Workman and Patrick G. Johnston

JCO Oct 10 2005: 7253–7256. [Full Text] [PDF]

ORIGINAL REPORTS
Genomics/Proteomics
	Differential Gene Expression in Ovarian Tumors Reveals Dusp 4 and Serpina 5 As Key Regulators for Benign Behavior of Serous Borderline Tumors
	Nathalie L.G. Sieben, Jan Oosting, Adrienne M. Flanagan, Jaime Prat, Guido M.J.M. Roemen, Sandra M. Kolkman-Uljee, Ronald van Eijk, Cees J. Cornelisse, Gert Jan Fleuren, and Manon van Engeland
	JCO Oct 10 2005: 7257–7264. First published on Aug 8 2005; 10.1200/JCO.2005.02.2541. [Abstract] [Full Text] [PDF]

Breast Cancer
	Gene Expression Profiles in Paraffin-Embedded Core Biopsy Tissue Predict Response to Chemotherapy in Women With Locally Advanced Breast Cancer
	Luca Gianni, Milvia Zambetti, Kim Clark, Joffre Baker, Maureen Cronin, Jenny Wu, Gabriella Mariani, Jaime Rodriguez, Marialuisa Carcangiu, Drew Watson, Pinuccia Valagussa, Roman Rouzier, W. Fraser Symmans, Jeffrey S. Ross, Gabriel N. Hortobagyi, Lajos Pusztai, and Steven Shak
	JCO Oct 10 2005: 7265–7277. First published on Sep 6 2005; 10.1200/JCO.2005.02.0818. [Abstract] [Full Text] [PDF]
	Breast Cancer Prognosis Determined by Gene Expression Profiling: A Quantitative Reverse Transcriptase Polymerase Chain Reaction Study
	E. Espinosa, J.A. Fresno Vara, A. Redondo, J.J. Sánchez, D. Hardisson, P. Zamora, F. Gómez Pastrana, P. Cejas, B. Martínez, A. Suárez, F. Calero, and M. González Barón
	JCO Oct 10 2005: 7278–7285. First published on Aug 29 2005; 10.1200/JCO.2005.01.4746. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Gene Expression Profile Predicts Patient Survival of Gastric Cancer After Surgical Resection
	Chiung-Nien Chen, Jen-Jen Lin, Jeremy J. W. Chen, Po-Huang Lee, Ching-Yao Yang, Min-Liang Kuo, King-Jen Chang, and Fon-Jou Hsieh
	JCO Oct 10 2005: 7286–7295. First published on Sep 6 2005; 10.1200/JCO.2004.00.2253. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Molecular Classification of Multiple Myeloma: A Distinct Transcriptional Profile Characterizes Patients Expressing CCND1 and Negative for 14q32 Translocations
	Luca Agnelli, Silvio Bicciato, Michela Mattioli, Sonia Fabris, Daniela Intini, Donata Verdelli, Luca Baldini, Fortunato Morabito, Vincenzo Callea, Luigia Lombardi, and Antonino Neri
	JCO Oct 10 2005: 7296–7306. First published on Aug 29 2005; 10.1200/JCO.2005.01.3870. [Abstract] [Full Text] [PDF]

Lung Cancer
	Functional FGFR4 Gly388Arg Polymorphism Predicts Prognosis in Lung Adenocarcinoma Patients
	Monica Spinola, Vera Leoni, Carmen Pignatiello, Barbara Conti, Fernando Ravagnani, Ugo Pastorino, and Tommaso A. Dragani
	JCO Oct 10 2005: 7307–7311. First published on Aug 1 2005; 10.1200/JCO.2005.17.350. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Loss of Heterozygosity for Chromosomes 1p and 16q Is an Adverse Prognostic Factor in Favorable-Histology Wilms Tumor: A Report From the National Wilms Tumor Study Group
	Paul E. Grundy, Norman E. Breslow, Sierra Li, Elizabeth Perlman, J. Bruce Beckwith, Michael L. Ritchey, Robert C. Shamberger, Gerald M. Haase, Giulio J. D'Angio, Milton Donaldson, Max J. Coppes, Marcio Malogolowkin, Patricia Shearer, Patrick R.M. Thomas, Roger Macklis, Gail Tomlinson, Vicki Huff, and Daniel M. Green
	JCO Oct 10 2005: 7312–7321. First published on Aug 29 2005; 10.1200/JCO.2005.01.2799. [Abstract] [Full Text] [PDF]
	Inferring a Tumor Progression Model for Neuroblastoma From Genomic Data
	Sven Bilke, Qing-Rong Chen, Frank Westerman, Manfred Schwab, Daniel Catchpoole, and Javed Khan
	JCO Oct 10 2005: 7322–7331. First published on Sep 6 2005; 10.1200/JCO.2005.03.2821. [Abstract] [Full Text] [PDF]

REVIEW ARTICLES
	Roadmap for Developing and Validating Therapeutically Relevant Genomic Classifiers
	Richard Simon
	JCO Oct 10 2005: 7332–7341. First published on Sep 6 2005; 10.1200/JCO.2005.02.8712. [Abstract] [Full Text] [PDF]
	Pharmacogenomic Discovery Approaches: Will the Real Genes Please Stand Up?
	Richard A. Walgren, Melissa A. Meucci, and Howard L. McLeod
	JCO Oct 10 2005: 7342–7349. First published on Sep 6 2005; 10.1200/JCO.2005.03.0825. [Abstract] [Full Text] [PDF]
	Molecular Classification and Molecular Forecasting of Breast Cancer: Ready for Clinical Application?
	James D. Brenton, Lisa A. Carey, Ahmed Ashour Ahmed, and Carlos Caldas
	JCO Oct 10 2005: 7350–7360. First published on Sep 6 2005; 10.1200/JCO.2005.03.3845. [Abstract] [Full Text] [PDF]

GLOSSARY

Glossary

JCO Oct 10 2005: 7365–7374. [PDF]

CORRESPONDENCE

Persistent Residual Disease in t(11;18)(q21;q21) Positive Gastric Mucosa-Associated Lymphoid Tissue Lymphoma Treated With Chemotherapy or Rituximab

Antonio Salar, Beatriz Bellosillo, Sergio Serrano, and Carlos Besses

JCO Oct 10 2005: 7361–7362. [Full Text] [PDF]

In Reply:

Daniele Laszlo, Alberto Agazzi, Giancarlo Pruneri, Francesco Bertoni, Liliana Calabrese, and Giovanni Martinelli

JCO Oct 10 2005: 7362–7363. [Full Text] [PDF]

Chemosensitivity and Chemoresistance Testing

Maurie Markman

JCO Oct 10 2005: 7363–7364. [Full Text] [PDF]

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